'Jurassic Park' technique resurrects extinct DNA
In an echo of the film Jurassic Park, DNA from an extinct animal has been re-activated in the laboratory for the first time.
Scientists took genetic material from the  Tasmanian tiger – officially declared extinct 70 years ago – and  inserted it into mouse embryos where it played a role in developing  cartilage and future bone.
Dr Andrew Pask, from  the University of Melbourne in Australia, who led the research, said:  "This is the first time that DNA from an extinct species has been used  to induce a functional response in another living organism. As more and  more species of animals become extinct, we are continuing to lose  critical knowledge of gene function and their potential."
In the film Jurassic Park, dinosaurs are brought to  life by resurrecting their preserved DNA. Some scientists have  suggested bringing back the Tasmanian tiger using cloning technology  like that depicted in the movie. Others are sceptical, pointing out that  the DNA needed is unlikely to be well enough preserved.
The  new research proved that DNA from an extinct animal could be  resurrected. The 5ft-long Tasmanian tiger (Thylacinus cynocephalus), a  type of marsupial wolf, was hunted to extinction in the wild in the  early 1900s and the last captive specimen died in Tasmania's Hobart Zoo  in 1936. But some infant specimens were kept and preserved.
Dr  Pask's team took DNA fragments and selected an "enhancer" element  associated with a gene called Col2a1 that makes collagen. Although not a  gene in itself, the element helped the gene to function.
Placed into mouse embryos, the DNA was "switched on" and assisted the development of cartilage, the first step in making bone.
The  findings, published in the journal PLoS ONE, have enormous potential  for the understanding of the biology of extinct animals, say the  scientists.